Priest Lake Veterinary Hospital

News Letter from:
July 5, 2000


Many of our clients have had questions concerning tick borne diseases recently. I felt that it would be helpful to write a small article on the most common tick disease that we see in our practice.

Please e mail me at priestlake@mindspring.com if you would like to see other topics covered in future emails.

Sincerely,
Dr. Pennington





EHRLICHIOSIS


Erlichiosis is a disease caused by bacteria, Ehrlichia, that infect white blood cells and are transmitted by the bite of an infected tick.

The lone star tick, the American dog tick (or wood tick) and the deer tick (or black-legged tick) have been associated with ehrlichiosis. A tick can survive for 6 years with no nourishment other than water from the air.

The tick *can* transmit disease regardless of the length of attachment *if* it regurgitates stomach contents into the host's bloodstream. Often, this occurs when a tick is improperly removed (i.e., by compressing its body, rather than by using a tick remover or tweezers as close as possible to the mouth.)

The ticks, often no bigger than a pin head, become active and can spread disease any time of the year when the temperature is 40 degrees or more at ground level. Peak months for tick-borne diseases are June and July.

What are the symptoms of ehrlichiosis in humans?

Illness due to ehrlichiosis can be so mild that no medical care is sought or the illness can be severe and sometimes fatal. Symptoms are generally non-specific and other diagnoses may be considered. The more common complaints are fever, headache and muscle aches. Persons with ehrlichiosis also may experience loss of appetite, nausea and vomiting. A rash can occur but is usually not present.

What are the symptoms of ehrlichiosis in pets?

The disease typically courses through three stages. The first is the early or acute stage (which usually mimics a mild viral infection.) The signs in this stage may be very subtle and could go unnoticed. Without proper treatment the animal will go on to a subclinical (second) stage or may advance to the chronic (final) stage. During the acute stage most, if not all, damage is reversible and a full recovery is possible. It is during this stage that treatment is most effective, which emphasizes the need for early detection.

Once the chronic stage is reached, the rickettsial organism has taken up residence within the bone marrow. At this point the damage done is often irreversible. It is not unusual for dogs in this final stage to suffer massive internal hemorrhage, or succumb to sudden stroke, heart attack, renal failure, splenic rupture or liver failure, resulting in death. A peculiarity about the disease is these dogs often do not look or act as though they are in a terminal stage of disease until their final hour.



DETECTION OF EHRLICHIA


If there is any one element of this disease that makes it especially deadly, it is the ability it possesses to mimic other diseases. Perhaps the best description of ehrlichiosis is "the AIDS of the canine world". The detection of the disease has, so far, only been successfully accomplished through IFA (indirect fluorescent antibody test) which detects the presence of antibodies.

Regardless of the what the titer is, any positive should be considered indicative of infection and treated quickly and aggressively. A dog with a negative titer who has signs should still be treated, then re-tested at a later date.

Additionally, the severe depression of the immune system created by the disease opens the door to secondary bacterial infections and other complications. Because the onset of visible signs is likely to be gradual in the chronic phase and subtle in appearance, alertness to the following conditions is imperative in order to catch the disease while it is still treatable:

1.weakness
2.cough
3.labored breathing
4.fatigue
5.pneumonia
6.intermittent fever
7.arthritis
8.muscle wasting
9.discharge from nose or eye
10.depression



TREATMENT OF EHRLICHIOSIS


Due to the rapid spread and inadequate publicity the single biggest failure has been the failure to recognize and test for the disease. Perhaps the strongest recommendation that can be made is to eliminate ehrlichiosis first as a possible cause by treating with appropriate antibiotics to see if the animal responds. If an animal has any of the above signs an excellent path would be to take blood for a Indirect Fluorescent Antibody (IFA) test and start the animal on doxycycline immediately.

If Lyme disease is the suspect then we treat with doxycycline. Although some chronically-infected dogs may need steroid treatment, this should always be done in conjunction with doxycycline treatment and only as a last resort measure.

How can ehrlichiosis be prevented in people and their pets?

Persons spending time outdoors in tick-infested areas should take precautions against all tick borne diseases:

Wear light-colored clothing so ticks are easier to see. Wear long-sleeved shirts, long pants, socks and closed shoes (rather than sandals). Tuck shirts into pants and pant cuffs into the tops of socks. Walk in the center of paths, trails, or cleared or mowed areas to avoid brushing against vegetation. While in potential tick habitats, check yourself and companions every few hours and promptly remove any tick(s). Repellents also can be applied to discourage ticks from attaching to skin or clothing. Repellents containing up to 30 percent DEET have been shown to be effective in repelling ticks. Use these products cautiously on children and supervise application. Repellents containing permethrin can be sprayed on clothing. Regardless of the type of repellent used, be sure to follow the manufacturer's directions. Do not overuse or misuse repellents. If possible, avoid areas known to be tick infested.

Pets should be protected with a preventic collar or frontline topical or spray (spray provides better barrier protection) when they will be in areas that are tick infested.

How should an attached tick be removed?

Grasp the tick as close to the skin's surface as possible with tweezers and pull straight back in a slow, steady motion without twisting. Avoid crushing the tick's body because it may contain infectious fluid. If you do not have tweezers, you can use your fingertips but they should be covered (with tissue paper or gloves). After the tick is removed, wash the bite site and your hands with soap and water and apply a disinfectant or antibiotic ointment to the site.

Best Regards,
Dr. Pennington



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